Changes in Locomotor Muscle Activity After Treadmill Training in Subjects With Incomplete Spinal Cord Injury
Changes in Locomotor Muscle Activity After Treadmill Training in Subjects With Incomplete Spinal Cord Injury
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DOI：
10.1152/jn.91131.2008
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发表时间：
2009-02-01
影响因子：
2.5
通讯作者：
Yang, Jaynie F.
中科院分区：
文献类型：
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作者：
Gorassini, Monica A.;Norton, Jonathan A.;Yang, Jaynie F.
Gorassini MA，Norton JA，Nevett-Duchcherer J，Roy FD，Yang JF.不完全性脊髓损伤受试者踏车训练后运动肌活动的变化。神经生理学杂志101：969-979，2009年。首次发表于2008年12月10日; doi：10.1152/jn.91131.2008。不完全性脊髓损伤后强化跑台训练可改善功能性步行能力。为了确定与步行改善相关的肌肉激活模式的变化，我们在训练前后测量了17名不完全脊髓损伤患者在类似步行条件下的腿部肌肉肌电图（EMG）。与跑步机训练无效的受试者（无应答者）相比，在地上行走最终获得功能改善的受试者（应答者）之间观察到特定差异。虽然两组在跑步机上都发展出了更有规律、更少阵挛的EMG模式，但只有反应者的胫骨前肌和腿筋肌显示出EMG激活的增加。同样，只有反应者表现出短阵持续时间和近端（腘绳肌和股四头肌）肌肉活动的共同收缩减少。令人惊讶的是，与无反应者不同，反应者的近端肌肉活动比以类似速度和体重支持水平行走的未受伤对照受试者大三到四倍，这表明损伤后修改肌肉激活模式的能力可以预测受试者进一步补偿运动训练的能力。总之，特定肌肉的EMG活动的量的增加和持续时间的减少与能够在不完全脊髓损伤后改变肌肉活动模式的受试者在跑步机训练后的步行技能的功能恢复相关。
Gorassini MA, Norton JA, Nevett-Duchcherer J, Roy FD, Yang JF. Changes in locomotor muscle activity after treadmill training in subjects with incomplete spinal cord injury. J Neurophysiol 101: 969-979, 2009. First published December 10, 2008; doi: 10.1152/jn.91131.2008. Intensive treadmill training after incomplete spinal cord injury can improve functional walking abilities. To determine the changes in muscle activation patterns that are associated with improvements in walking, we measured the electromyography (EMG) of leg muscles in 17 individuals with incomplete spinal cord injury during similar walking conditions both before and after training. Specific differences were observed between subjects that eventually gained functional improvements in overground walking (responders), compared with subjects where treadmill training was ineffective (nonresponders). Although both groups developed a more regular and less clonic EMG pattern on the treadmill, it was only the tibialis anterior and hamstring muscles in the responders that displayed increases in EMG activation. Likewise, only the responders demonstrated decreases in burst duration and cocontraction of proximal (hamstrings and quadriceps) muscle activity. Surprisingly, the proximal muscle activity in the responders, unlike nonresponders, was three- to fourfold greater than that in uninjured control subjects walking at similar speeds and level of body weight support, suggesting that the ability to modify muscle activation patterns after injury may predict the ability of subjects to further compensate in response to motor training. In summary, increases in the amount and decreases in the duration of EMG activity of specific muscles are associated with functional recovery of walking skills after treadmill training in subjects that are able to modify muscle activity patterns following incomplete spinal cord injury.