CONCENTRATIONS OF LEAD IN MATERNAL BLOOD, CORD BLOOD, AND BREAST-MILK
CONCENTRATIONS OF LEAD IN MATERNAL BLOOD, CORD BLOOD, AND BREAST-MILK
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DOI：
10.1136/adc.60.8.756
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发表时间：
1985-01-01
影响因子：
5.2
通讯作者：
LIM, HH
中科院分区：
文献类型：
--
作者：
ONG, CN;PHOON, WO;LIM, HH
采用石墨原子吸收分光光度法测定了114名非职业性铅接触妇女的母血、脐带血和母乳中铅含量。母血、脐带血和母乳中铅的平均浓度分别为0.7、0.55和0.23 μ mol/l。母体血与脐带血之间存在显著相关性（r = 0.63）。母体血液和母乳之间的相关性较低（r = 0.29）。这些结果表明，铅自由地穿过胎盘屏障从母亲到胎儿，这种重金属从母体组织转移到母乳是可能的，但代谢机制更为复杂。此外，还对9名哺乳期妇女的母乳中铅浓度进行了纵向研究。结果表明，泌乳早期母乳中铅含量无明显变化。
Lead concentrations in maternal blood, umbilical cord blood, and breast milk from 114 women who were not occupationally exposed to lead were determined by graphite atomic absorption spectrophotometry. The mean concentrations of lead in maternal blood, umbilical cord blood and brest milk were 0.7, 0.55 and 0.23 .mu.mol/l, respectively. A significant correlation was observed between maternal and umbilical cord blood (r = 0.63). A lower correlation was noted between maternal blood and breast milk (r = 0.29). These results suggest that lead freely crosses the placental barrier from mother to fetus and the transfer of this heavy metal from maternal tissues to breast milk is possible, but the metabolic mechanisms are more complicated. In addtion, a longitudinal study was conducted of concentrations of lead in breast milk in nine lactating women. Results suggested no significant change in the content of lead in brest milk during early lactation.