Sensitivity to interaural temporal disparities of low- and high-frequency neurons in the superior olivary complex .1. Heterogeneity of responses
Sensitivity to interaural temporal disparities of low- and high-frequency neurons in the superior olivary complex .1. Heterogeneity of responses
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DOI：
10.1152/jn.1997.78.3.1222
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发表时间：
1997-09-01
影响因子：
2.5
通讯作者：
Fitzpatrick, DC
中科院分区：
文献类型：
--
作者：
Batra, R;Kuwada, S;Fitzpatrick, DC
耳间时间差异 (ITD) 是沿方位角定位声音的线索。听众可以在低频声音的精细结构以及高频声音的包络中检测到 ITD。对 ITD 的敏感性源自上橄榄复合体 (SOC)、内侧和外侧上橄榄体（分别为 MSG 和 LSO）的主核。这种敏感性被认为是由于 MSO 神经元的双侧兴奋汇聚以及 LSO 神经元的同侧兴奋与对侧抑制汇聚而产生的。在这里，我们研究 SOC 中的神经元对 ITD 的敏感性是否可以通过这两种机制之一来充分解释。在未麻醉兔子的 SOC 中对单个和多个单元 (n = 124) 进行了细胞外研究。我们在低频的精细结构中发现了对 ITD 敏感的单元（
Interaural temporal disparities (ITDs) are a cue for localization of sounds along the azimuth. Listeners can detect ITDs in the fine structure of low-frequency sounds and also in the envelopes of high-frequency sounds. Sensitivity to ITDs originates in the main nuclei of the superior olivary complex (SOC), the medial and lateral superior olives (MSG and LSO, respectively). This sensitivity is believed to arise from bilateral excitation converging on neurons of the MSO and ipsilateral excitation converging with contralateral inhibition on neurons of the LSO. Here we investigate whether the sensitivity of neurons in the SOC to ITDs can be adequately explained by one of these two mechanisms. Single and multiple units (n = 124) were studied extracellularly in the SOC of unanesthetized rabbits. We found units that were sensitive to ITDs in the fine structure of low-frequency (