SYNTHESIS OF (ALPHA,ALPHA-DIFLUOROALKYL)PHOSPHONATES BY DISPLACEMENT OF PRIMARY TRIFLATES
SYNTHESIS OF (ALPHA,ALPHA-DIFLUOROALKYL)PHOSPHONATES BY DISPLACEMENT OF PRIMARY TRIFLATES
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DOI：
10.1021/jo00075a005
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发表时间：
1993-11-05
影响因子：
3.6
通讯作者：
SLOSS, DG
中科院分区：
文献类型：
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作者：
BERKOWITZ, DB;EGGEN, M;SLOSS, DG
简单的伯烷基三氟酸盐和由几种单糖衍生的烷基三氟酸盐被二乙基（二氟甲基）膦酸盐完全取代，在-78摄氏度下，几分钟内就能得到相应的（α， α -二氟烷基）膦酸盐。
Simple primary alkyl triflates and those derived from several monosaccharides are cleanly displaced by diethyl (lithiodifluoromethyl)phosphonate to provide the corresponding (alpha,alpha-difluoroalkyl)phosphonates in minutes at -78-degrees-C.