METHODOLOGY AND BASIC PROBLEMS RELATED TO BLOOD-FLOW STUDIES IN THE HUMAN-FETUS

METHODOLOGY AND BASIC PROBLEMS RELATED TO BLOOD-FLOW STUDIES IN THE HUMAN-FETUS
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DOI:
10.1016/0301-5629(84)90167-4
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发表时间:
1984-01-01
影响因子:
2.9
通讯作者:
KRISTOFFERSEN, K
KRISTOFFERSEN, K
中科院分区:
医学3区
文献类型:
--
作者:
EIKNES, SH;MARSAL, K;KRISTOFFERSEN, K

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建立了一种无创测量胎儿血流的方法。该方法结合实时超声与2 MHz脉冲多普勒技术。根据多普勒频谱估计的血流速度和实时图像中测量的血管直径计算血流。应用时间距离记录来测量胎儿主动脉脉动直径的变化。该方法被证明具有良好的准确性和重现性时,在体外实验中进行测试,并在与动物电磁流量测量比较。分析了可能的误差来源,并提出了尽量减少误差风险的建议。
A method was developed for noninvasive measurement of human fetal blood flow. The method combines real-time ultrasonography with 2 MHz pulsed Doppler technique. The blood flow is calculated from the blood velocity, estimated from the Doppler spectrum, and the vessel diameter, measured in the real-time image. Time-distance recording was applied for measurements of the pulsatile diameter changes in the fetal aorta. The method proved to possess a good accuracy and reproducibility when tested in vitro experiments and in a comparison with electromagnetic flow measurements in animals. Possible sources of error were analyzed and recommendations for minimizing the risk of errors are presented.