Edinger-Westphal neurons that project to spinal cord contain substance P.
Edinger-Westphal neurons that project to spinal cord contain substance P.
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投射到脊髓的 Edinger-Westphal 神经元含有 P 物质。
DOI：
10.1016/0304-3940(83)90253-7
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发表时间：
1983
影响因子：
2.5
通讯作者：
Foote,WE
中科院分区：
文献类型：
--
作者：
Phipps,BS;Maciewicz,R;Sandrew,BB;Poletti,CE;Foote,WE
结合逆行转运和免疫细胞化学方法，以确定是否Edinger-Westphal神经元投射到脊髓也表现出P物质样免疫反应性（SPLI）。将辣根过氧化物酶（HRP）大量注射到颈部和腰部肿大处，逆行标记整个Edinger-Westphal复合体（EW）长度的细胞。几乎所有的HRP标记的EW神经元也染色SPLI，证据表明，EW是一个直接的P物质通路的起源，连接吻侧中脑与脊髓。
Combined retrograde transport and immunocytochemical methods were used to determine whether Edinger-Westphal neurons projecting to spinal cord also demonstrate substance P-like immunoreactivity (SPLI). Large injections of horseradish peroxidase (HRP) into cervical and lumbar enlargements retrogradely labeled cells throughout the length of the Edinger-Westphal complex (EW). Nearly all HRP-labeled EW neurons also stained for SPLI, evidence that EW is the origin of a direct substance P pathway linking rostral mesencephalon with spinal cord.