EPIDEMIC OF AIDS RELATED VIRUS (HTLV-III/LAV) INFECTION AMONG INTRAVENOUS DRUG-ABUSERS
EPIDEMIC OF AIDS RELATED VIRUS (HTLV-III/LAV) INFECTION AMONG INTRAVENOUS DRUG-ABUSERS
复制标题
DOI：
10.1136/bmj.292.6519.527
复制
发表时间：
1986-02-22
影响因子：
105.7
通讯作者：
BRETTLE, RP
中科院分区：
文献类型：
--
作者：
ROBERTSON, JR;BUCKNALL, ABV;BRETTLE, RP
对参加苏格兰[英国]全科诊所的164名静脉吸毒者的储存血液样本进行了HTLV-III LAV(人类T细胞淋巴组织病毒III型/淋巴结病相关病毒)感染检测。在接受治疗的患者中，83人(51%)血清呈阳性，这远远高于英国和欧洲其他地方报告的流行率以及在纽约市[美国纽约]观察到的方法。采集阴性血清样本的时间和持续使用药物的时间表明，目前该人群中可能有多达85%的人被感染。这种感染在1983年底和1984年初流行，此后成为地方性流行病。共用针头和注射器的做法与血清阳性有关，再加上几乎完全静脉注射海洛因和其他行为模式，可能解释了该地区HTLV-III/LAV感染的高流行率。需要迅速和积极的干预措施来控制感染的传播。
Stored blood samples from 164 intravenous drug abusers who attended a Scottish [UK] general practice were tested for HTLV-III LAV (human T cell lymphotropic virus type III/lymphadenopathy associated virus) infection. Of those treated, 83 (51%) were seropositive, which is well above the prevalence reported elsewhere in Britain and Europe and approaches that observed in New York City [New York, USA]. The timing of taking samples of negative sera and continued drug use suggest that as many as 85% of this population might now be infected. The infections became epidemic in late 1983 and early 1984, thereafter becoming endemic. The practice of sharing needles and syringes correlated with seropositivity, which, combined with the almost exclusive intraveous use of heroin and other behavioral patterns, may explain the high prevalence of HTLV-III/LAV infection in the area. Rapid and aggressive intervention is needed to control the spread of infections.