Long non-coding RNAs and their biological roles in plants.
Long non-coding RNAs and their biological roles in plants.
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DOI：
10.1016/j.gpb.2015.02.003
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发表时间：
2015-06
期刊：
影响因子：
--
通讯作者：
Hu S
中科院分区：
文献类型：
--
作者：
Liu X;Hao L;Li D;Zhu L;Hu S
随着基因组学和生物信息学的发展，特别是高通量测序技术的广泛应用，越来越多的蛋白质编码单位被发现。这种RNA分子被称为非蛋白质编码RNA（npcRNA或ncRNA）。其中，长npcRNA或ncRNA（lnpcRNA或lncRNA）代表长于200个核苷酸的不同类别的转录物。近年来，lncRNA被认为是许多重要生物过程的重要调节因子。在植物中，虽然大量的lncRNA转录本已被预测和确定在少数物种中，我们目前的知识仍然有限，他们的生物学功能。本文综述了近几年来其在植物中的鉴定、特征、分类、生物信息学、资源以及生物学功能的研究进展。
With the development of genomics and bioinformatics, especially the extensive applications of high-throughput sequencing technology, more transcriptional units with little or no protein-coding potential have been discovered. Such RNA molecules are called non-protein-coding RNAs (npcRNAs or ncRNAs). Among them, long npcRNAs or ncRNAs (lnpcRNAs or lncRNAs) represent diverse classes of transcripts longer than 200 nucleotides. In recent years, the lncRNAs have been considered as important regulators in many essential biological processes. In plants, although a large number of lncRNA transcripts have been predicted and identified in few species, our current knowledge of their biological functions is still limited. Here, we have summarized recent studies on their identification, characteristics, classification, bioinformatics, resources, and current exploration of their biological functions in plants.