Contribution of diet and other factors to the levels of selected polyfluorinated compounds: Data from NHANES 2003-2008

Contribution of diet and other factors to the levels of selected polyfluorinated compounds: Data from NHANES 2003-2008
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DOI:
10.1016/j.ijheh.2013.03.008
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发表时间:
2014-01-01
影响因子:
6
通讯作者:
Jain, Ram B.
Jain, Ram B.
中科院分区:
医学2区
文献类型:
--
作者:
Jain, Ram B.

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评估了饮食和选定的危险因素对四种多氟化合物水平的影响。数据来自2003-2008年全国健康和营养检查调查。饮食因素占解释变异的10.4% ~ 21.2%。牛奶摄入量与全氟壬烷酸(PFNA)呈正相关(p < 0.01),与全氟辛酸(PFOA)和全氟辛烷磺酸(PFOS)呈负相关(p < 0.01)。肉和鱼的食用量与PFNA和PFOS呈显著正相关(p < 0.01)。非酒精饮料的消费量与PFNA和PFOA呈正相关(p < 0.01)。全氟辛烷磺酸水平随着酒精饮料消费量的增加而增加(p < 0.01)。饮酒总量与PFNA呈正相关(p < 0.01)。全氟辛烷磺酸和全氟辛烷磺酸的水平都随着摄入咖啡因总量的增加而下降。脂肪消耗总量与PFNA呈负相关,与PFOS呈正相关。摄入的总热量与全氟己烷磺酸和全氟辛烷磺酸呈负相关,但与全氟辛烷磺酸呈正相关。新的研究发现,血清胆固醇与PFNA、PFOA和PFOS呈正相关(p < 0.01)。血清白蛋白水平与PFHxS呈负相关,与PFOA、PFOS呈正相关。男性的四种pfc水平明显高于女性,而墨西哥裔美国人的四种pfc水平低于其他种族/民族。随着家庭收入的增加,所有四种pfc的水平都有所增加。体质指数与PFNA呈负相关,与PFOA呈正相关。在2003-2008年调查期间,全氟辛烷磺酸的水平在统计上有显著下降。(C) 2013爱思唯尔有限公司版权所有。
Contribution of diet and selected risk factors to the levels of four polyfluorinated compounds was evaluated. Data from National Health and Nutrition Examination Survey for the years 2003-2008 were used. Dietary factors accounted for 10.4% to 21.2% of the explained variation. Amount of milk consumed was found to be positively associated (p < 0.01) with perfluorononanoic acid (PFNA) but negatively associated with perfluorooctanoate (PFOA) and perfluorooctane sulfonate (PFOS) (p < 0.01). Amount of meat and fish consumed was positively associated (p < 0.01) with PFNA and PFOS. Amount of non-alcoholic beverages consumed was positively associated (p < 0.01) with PFNA and PFOA. Levels of PFOS increased (p < 0.01) with increase in the amount of alcoholic beverages consumed. Total amount of alcohol consumed was positively associated (p < 0.01) with PFNA. Levels of both PFOA and PFOS decreased with increase in total amount of caffeine consumed. Total amount of fat consumed was negatively associated with PFNA and positively associated with PFOS. Total calories consumed were negatively associated with perfluorohexane sulfonate (PFHxS) and PFOS but positively associated with PFNA. New to this study, positive correlations (p < 0.01) between serum cholesterol and PFNA, PFOA, and PFOS were found. Serum albumin levels were negatively correlated with PFHxS but positively correlated with PFOA and PFOS. Males had statistically significantly higher levels of all four PFCs as compared to females and Mexican Americans had the lowest levels Of all four PFCs than other race/ethnic groups. Levels of all four PFCs increased with increase in family income. Body mass index was negatively correlated with PFNA but positively associated with PFOA. There was a statistically significant decrease in the levels of PFOS over survey years 2003-2008. (C) 2013 Elsevier GmbH. All rights reserved.