The prevalence of the metabolic syndrome in Greece: the MetS-Greece Multicentre Study
The prevalence of the metabolic syndrome in Greece: the MetS-Greece Multicentre Study
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DOI：
10.1111/j.1463-1326.2004.00409.x
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发表时间：
2005-07-01
影响因子：
5.8
通讯作者：
Mikhailidis, DP
中科院分区：
文献类型：
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作者：
Athyros, VG;Bouloukos, VI;Mikhailidis, DP
背景：国家胆固醇教育计划专家小组（NCEP）的第三份报告（ATP III）强调了识别和治疗代谢综合征（MetS）患者对于预防心血管疾病（CVD）和进展为糖尿病的重要性。根据NCEP ATP 111的定义，关于MetS在欧洲，特别是希腊的流行情况的信息有限。目的：估计MetS在希腊的患病率，MetS-Greece研究。设计和参与者：对希腊成年人的代表性样本（4153名18岁以上的参与者）进行横断面分析。一组由军事人员组成（n = 300），另一组由希腊穆斯林社区组成（n = 300）进行比较。总共有4753名受试者被纳入最终分析。结果：所有受试者均为白人男性（49%）和女性（51%），分别生活在城市（n = 2243, 54%）、半城市（n = 1038, 25%）和农村（n = 872, 21%）地区。年龄标准化的met患病率为23.6%[95%可信区间（Cl）： 22.4-25.1%]。这在男性（24.2%,95% Cl: 22.3-25.2%）和女性（22.8%,95% Cl: 21.4-25.0%）中相似（p = 0.3）。男女患病率随年龄增长而增加，19-29岁的参与者为4.8%，70岁以上的参与者为43% （p < 0.0001）。与19-29岁年龄组相比，70岁年龄组MetS的优势比增加了14.7倍（p < 0.0001）。大多数MetS患者有三种症状（61%），29%有四种症状，10%有五种症状。腹部肥胖（82%）和动脉高血压（78%）是两性中最常见的异常。高饱和脂肪饮食的希腊穆斯林社区的met患病率最高（35.2%,95% Cl: 30.4-40.3%），而高体力活动水平和饮食“接近”地中海的军人群体的met患病率最低（9.4%,95% Cl: 6.2-13.1%）。根据2001年的人口普查，大约有230万希腊人可能患有大都会综合症。结论：这些结果表明MetS在希腊成年人中非常普遍。这可能对心血管疾病的发病率有重大影响。必须紧急开展促进健康饮食、低热量摄入和体育活动的工作。
Background: The Third Report (ATP III) of the National Cholesterol Education Program Expert Panel (NCEP) highlighted the importance of identifying and treating patients with the metabolic syndrome (MetS) to prevent cardiovascular disease (CVD) and progression to diabetes mellitus. Limited information is available about the prevalence of MetS, as defined by the NCEP ATP 111, in Europe, especially in Greece.Objective: To estimate the prevalence of the MetS in Greece, The MetS-Greece Study.Design and participants: A cross-sectional analysis of a representative sample of Greek adults (4153 participants older than 18 years). One group consisting of military personnel (n = 300) and another one from a Greek Muslim Community (n = 300) were used for comparison. In all, 4753 subjects were included in the final analysis.Results: All subjects from the general population were Caucasian men (49%) and women (51%), living in urban (n = 2243, 54%), semi-urban (n = 1038, 25%) and rural (n = 872, 21%) areas. The age-standardized prevalence of the MetS was 23.6% [95% confidence interval (Cl): 22.4-25.1%]. This was similar in men (24.2%, 95% Cl: 22.3-25.2%) and women (22.8%, 95% Cl: 21.4-25.0%) (p = 0.3). The prevalence increased with age in both sexes, 4.8% among participants aged 19-29 years and 43% for participants over 70 years old (p for trend < 0.0001). There was a 14.7-fold increase in odds ratio for having MetS in the age group > 70 years old compared with that of 19-29 years old (p < 0.0001) Most of those with MetS had three components of the syndrome (61%), 29% had four and 10% had all five components. Abdominal obesity (82%) and arterial hypertension (78%) were the most common abnormalities in both sexes. The Greek Muslim Community, on a high-saturated fat diet, had the highest prevalence of the MetS (35.2%, 95% Cl: 30.4-40.3%), and the military group, with a high physical activity level and a diet 'close' to Mediterranean, had the lowest (9.4%, 95% Cl: 6.2-13.1%). According to the 2001 Census, about 2.3 million Greeks may have the MetS.Conclusions: These results show that the MetS is highly prevalent in the Greek adult population. This may have major implications for the incidence of CVD. Promoting healthy diets, low caloric intake and physical activity must be urgently undertaken.