Diffusion-weighted magnetic resonance imaging: theory and potential applications to child neurology.
Diffusion-weighted magnetic resonance imaging: theory and potential applications to child neurology.
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DOI：
10.1016/s1071-9091(99)80035-7
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发表时间：
1999-06-01
影响因子：
2.7
通讯作者：
Moseley, M E
中科院分区：
文献类型：
--
作者：
Beaulieu, C;D'Arceuil, H;Moseley, M E
磁共振成像（MRI）是研究儿童神经系统疾病的一种极好的工具。弥散加权MRI （DWI）对水在组织中的扩散（或分子位移）很敏感。本文的目的是简要介绍DWI背后的基本理论，并讨论其在儿童神经系统疾病中的潜在应用。我们证明DWI是一种检测急性脑损伤的敏感技术，它非常适合监测大脑发育，特别是髓鞘形成和白质变化。
Magnetic resonance imaging (MRI) is an excellent tool for the investigation of neurological disorders in children. Diffusion-weighted MRI (DWI) is sensitive to the diffusion (or molecular displacement) of water in tissue. The purpose of this article is to describe briefly the basic theory behind DWI and to discuss its potential applications to neurological disorders in children. We demonstrate that DWI is a sensitive technique for the detection of acute brain injury, and that it is well suited for monitoring brain development, particularly myelination and white matter changes.