LEARNING TO SHAM FEED - BEHAVIORAL-ADJUSTMENTS TO LOSS OF PHYSIOLOGICAL POSTINGESTIONAL STIMULI
LEARNING TO SHAM FEED - BEHAVIORAL-ADJUSTMENTS TO LOSS OF PHYSIOLOGICAL POSTINGESTIONAL STIMULI
复制标题
DOI：
10.1152/ajpregu.1990.259.6.r1228
复制
发表时间：
1990-12-01
影响因子：
--
通讯作者：
SMITH, GP
中科院分区：
文献类型：
--
作者：
DAVIS, JD;SMITH, GP
当大鼠首次暴露于假喂食程序时，可以通过在每次假喂食试验之间穿插两次真实喂食试验来防止摄入浓缩（0.8 M蔗糖）溶液的逐渐增加。在这些条件下，假摄入量显着大于真实的摄入量，但显着小于连续第五次假喂养测试的摄入量。这一结果表明，有一个学习的负反馈信号的基础上的关联的味道和摄食后的影响0.8 M蔗糖下连续的假喂试验中消失。在测试过程中的摄取率的分析表明，条件负反馈信号的操作在第一个6分钟的假喂养测试，以下真正的喂养测试。无条件的负反馈信号的情况下出现的影响，从约6至约20分钟，在假喂养试验。
The progressive increase in intake of a concentrated (0.8 M sucrose) solution seen when rats are first exposed to the sham-feeding procedure can be prevented by interspersing two real-feeding tests between each sham-feeding test. Under these conditions, sham intake is significantly larger than real intake but significantly smaller than intake on the fifth consecutive sham-feeding test. This result indicates that there is a learned negative-feedback signal based on the association of the taste and postingestive effects of 0.8 M sucrose which extinguishes under consecutive sham-feeding tests. Analysis of the rate of ingestion during the tests revealed that the conditioned negative-feedback signal operates during the first 6 min of a sham-feeding test that follows real-feeding tests. The effect of the absence of an unconditional negative-feedback signal appears from approximately 6 to approximately 20 min during a sham-feeding test.