Reversals of association for Pap, colorectal, and prostate cancer testing among Hispanic and non-Hispanic black women and men.
Reversals of association for Pap, colorectal, and prostate cancer testing among Hispanic and non-Hispanic black women and men.
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西班牙裔和非西班牙裔黑人女性和男性中巴氏癌、结直肠癌和前列腺癌检测关联性的逆转。
DOI：
10.1158/1055-9965.epi-10-1226
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发表时间：
2011
期刊：
影响因子：
--
通讯作者：
Weitzen,SherryH
中科院分区：
文献类型：
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作者：
Rakowski,William;Clark,MelissaA;Rogers,MichelleL;Weitzen,SherryH
背景：几项研究发现，与非西班牙裔白人相比，西班牙裔和非西班牙裔黑人在癌症筛查测试中的调整OR在统计学上显著更高，尽管他们的粗百分比低于或约等于非西班牙裔白人。大多数文件是乳房X光检查。本文调查了巴氏涂片、结直肠和前列腺检查中这种未经调整的“反向关联”（RA）的患病率。我们还调查了大的百分比变化（LPC）的未调整ORs.Methods：数据来自2004/2006/2008行为危险因素监测系统（BRFSS）和2000/2003/2005/2008全国健康访谈调查（NHIS）。分析使用了一组一致的协变量。结果：RA是更常见的非西班牙裔黑人比西班牙裔，但西班牙裔有更多的LPC。RA和LPC在巴氏试验中的发生率高于结直肠和前列腺试验。然而，从BRFSS和NHIS的结果往往是不一致的。结论：应注意国家乳腺癌和宫颈癌早期检测计划，以及公共计划解决其他癌症，作为可能的贡献者RA和LPC。西班牙裔可能会在未来的数据分析中显示更多的RA。BRFSS和NHIS之间的差异也必须得到承认和explained.Impact：这项研究强调了需要警惕的分析结果，以确定种族/民族作为癌症筛查的相关性。结果还将注意力集中在多变量分析结果的各个方面，而不是OR和置信区间。©2011 AACR。
Background:Several studies have found that Hispanics and non-Hispanic blacks have statistically significantly higher adjusted OR for cancer screening tests compared to non-Hispanic whites, even though their crude percentages were lower than, or about equal to, those for the non-Hispanic whites. Most documentation is for mammography. This article investigates the prevalence of such unadjusted-to-adjusted “reversed associations” (RA) for Pap, colorectal, and prostate testing. We also investigate large percent changes (LPC) to the unadjusted ORs.Methods:Data were from the 2004/2006/2008 Behavioral Risk Factor Surveillance System (BRFSS) and the 2000/2003/2005/2008 National Health Interview Survey (NHIS). Analyses used a consistent set of covariates.Results:RAs were more common for non-Hispanic blacks than Hispanics, but Hispanics had a greater number of LPCs. RAs and LPCs occurred more often for Pap testing than colorectal and prostate testing. However, results from the BRFSS and NHIS were often not consistent.Conclusions:Attention should be given to the National Breast and Cervical Cancer Early Detection Program, as well as public programs addressing other cancers, as possible contributors to RAs and LPCs. Hispanics may show more RAs in analyses of future data. Discrepancies between the BRFSS and the NHIS also must be recognized and explained.Impact:This research highlights the need for vigilance regarding the results of analyses to identify race/ethnicity as a correlate of cancer screening. Results also direct attention to aspects of the results of multivariable analysis other than ORs and confidence intervals.Cancer Epidemiol Biomarkers Prev; 20(5); 876–89. ©2011 AACR.