Anesthetic management of a patient with 15q tetrasomy for dental treatment
Anesthetic management of a patient with 15q tetrasomy for dental treatment
复制标题
15q四体性牙科治疗患者的麻醉管理
DOI：
10.1016/j.bjane.2016.09.002
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发表时间：
2016
影响因子：
1.3
通讯作者：
Toshiaki Fujisawa
中科院分区：
文献类型：
--
作者：
Yuri Hase;Nobuhito Kemekura;Yukie Nitta;Toshiaki Fujisawa
背景和目的15q四体是一种染色体异常，是异质组外结构异常染色体的一部分。该综合征的特征是癫痫、中枢性张力低下、发育迟缓和智力残疾以及自闭症行为。这是第一个报告麻醉管理的病人与这种综合征。病例报告：我们对15q四体症患者进行全身麻醉治疗。结论适当的计划预防并发症，如癫痫发作和低张力，以及延迟麻醉复苏是必要的。具体来说，选择不引起癫痫发作的短效药物，加上适当的监测，导致15q四体患者的麻醉管理成功。
Background and objectives 15q tetrasomy is a chromosomal abnormality that is a part of the heterogeneous group of extra structurally abnormal chromosomes. This syndrome is characterized by epilepsy, central hypotonia, developmental delay and intellectual disability, and autistic behavior. This is the first report of the anesthetic management of a patient with this syndrome. Case report We administered general anesthesia for dental treatment in a patient with 15q tetrasomy. Conclusions Appropriate planning for the prevention of complications such as seizures and hypotonia, and for delayed emergence from anesthesia, is required. Specifically, choosing short-acting drugs that do not induce seizures, together with suitable monitoring, resulted in successful anesthetic management of the patient with 15q tetrasomy.