Lupus activity in pregnancy
Lupus activity in pregnancy
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DOI：
10.1016/j.rdc.2007.01.002
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发表时间：
2007-05-01
影响因子：
2.3
通讯作者：
Clowse, Megan E. B.
中科院分区：
文献类型：
--
作者：
Clowse, Megan E. B.
怀孕的妇女与系统性红斑狼疮（SLE）可合并狼疮活动和怀孕事故。最近的大多数研究发现，狼疮活动在怀孕期间增加，可能是由于维持怀孕所需的激素变化而加剧的。狼疮活动的增加反过来又会增加不良妊娠结局的风险，包括死胎、早产、低出生体重和先兆子痫。幸运的是，大多数SLE患者的妊娠是成功的。然而，妊娠和SLE活动之间的相互作用可导致母亲和婴儿的并发症。
Pregnancy in a woman with systemic lupus erythematosus (SLE) can be complicated by both lupus activity and pregnancy mishaps. The majority of recent studies found an increase in lupus activity during pregnancy, perhaps exacerbated by hormonal shifts required to maintain pregnancy. Increased lupus activity, in turn, prompts an elevated risk for poor pregnancy outcomes, including stillbirth, preterm birth, low birth weight, and preeclamspsia. Fortunately, the majority of pregnancies in women with SLE are successful. However, the interaction between pregnancy and SLE activity can lead to complications for both mother and baby.