The three-dimensional dose distribution of 125I seeds in tissue.

The three-dimensional dose distribution of 125I seeds in tissue.
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125I粒子在组织中的三维剂量分布。

DOI:
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发表时间:
1983
影响因子:
3.5
通讯作者:
H. Scharfenberǵ
H. Scharfenberǵ
中科院分区:
工程技术2区
文献类型:
--
作者:
G. Hartmann;W. Schlegel;H. Scharfenberǵ

文献摘要

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用125I粒子对脑肿瘤进行放射治疗需要对粒子的整个三维剂量分布有精确的了解。假设一个经各向异性因素修正的点源分布,计算了吸收能量,并与7LiF热释光剂量计的测量结果进行了比较。测量是在空气和混合- d中进行的。在垂直于种子轴的剂量的计算和测量之间,发现平均相对差为5%。由此得出结论,吸收剂量在组织中的整个三维分布可以用一个简单的公式来确定,该公式能够以6%的不确定度计算任何感兴趣点的吸收剂量。
The radiation treatment of brain tumours with 125I seeds requires a precise knowledge of the entire three-dimensional dose distribution of the seed. Assuming a point source distribution modified by an anisotropic factor, the absorbed energy is calculated and compared with measurements obtained using 7LiF thermoluminescence dosemeters. The measurements are carried out in air and in Mix-D. A mean relative difference of 5% is found between calculation and measurement of the dose perpendicular to the seed axis. It is concluded that the entire three-dimensional distribution of absorbed dose in tissue can be determined by a simple formula, which enables the calculation of absorbed dose at any point of interest with an uncertainty of 6%.