Measuring depression at the end of life: is the Hamilton Depression Rating Scale a valid instrument?
Measuring depression at the end of life: is the Hamilton Depression Rating Scale a valid instrument?
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DOI：
10.1177/1073191108320415
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发表时间：
2009-03
期刊：
影响因子：
3.8
通讯作者：
Breitbart W
中科院分区：
文献类型：
--
作者：
Olden M;Rosenfeld B;Pessin H;Breitbart W
临终抑郁是一种常见的心理健康问题，对生活质量和临终决策有严重影响。本研究调查了汉密尔顿抑郁量表(HAM-D)这一最常用的抑郁症测量工具的信度和效度，对422名住在姑息疗养院的晚期癌症患者进行了测试。根据DSM-IV(SCID-I/NP抑郁模块)的结构化临床访谈，HAM-D对抑郁症的诊断显示出高度的信度和同时效度。ROC分析产生了0.91的AUC，表明有很高的敏感性和特异性。收敛效度是通过与几种痛苦测量(例如，绝望、急死欲望、自杀意念)的强相关来建立的。因素分析产生了四个因素(焦虑、抑郁情绪、失眠和躯体症状)，这四个因素可以解释42%的方差。对评估晚期癌症患者抑郁的意义进行了讨论。
Depression at the end of life is a common mental health issue with serious implications for quality of life and end of life decision making. This study investigated the reliability and validity of one of the most frequently used measures of depression, the Hamilton Depression Rating Scale (HAM-D) in 422 patients with terminal cancer admitted to a palliative care hospital. The HAM-D demonstrated high reliability and concurrent validity with a diagnosis of depression, based on Structured Clinical Interview for DSM-IV (SCID-I/NP Depression Module). ROC analyses generated an AUC of .91, indicating high sensitivity and specificity. Convergent validity was established through strong correlations with several measures of distress (e.g., hopelessness, desire for hastened death, suicidal ideation). Factor analysis generated four factors (anxiety, depressed mood, insomnia, and somatic symptoms) that accounted for 42% of the variance. Implications for assessing depression in patients with terminal cancer are discussed.
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影响因子：
4.2
作者：
Carver, CS;Smith, RG;Derhagopian, RP
通讯作者：
Derhagopian, RP
影响因子：
7
作者：
CARROLL, BT;KATHOL, RG;CLAMON, GH
通讯作者：
CLAMON, GH
DOI：
10.1023/b:joba.0000045340.38371.04
发表时间：
2004-12-01
影响因子：
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作者：
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通讯作者：
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影响因子：
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作者：
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通讯作者：
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影响因子：
158.5
作者：
Ganzini, L;Johnston, WS;Lee, MA
通讯作者：
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