A Case-Control Study to Estimate the Effectiveness of Maternal Pertussis Vaccination in Protecting Newborn Infants in England and Wales, 2012-2013
A Case-Control Study to Estimate the Effectiveness of Maternal Pertussis Vaccination in Protecting Newborn Infants in England and Wales, 2012-2013
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DOI：
10.1093/cid/ciu821
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发表时间：
2015-02-01
影响因子：
11.8
通讯作者：
Ramsay, Mary
中科院分区：
文献类型：
--
作者：
Dabrera, Gavin;Amirthalingam, Gayatri;Ramsay, Mary
背景。感染百日咳的婴儿面临严重临床疾病和死亡的风险。随着全国百日咳通报数量的增加，包括英国在内的一些国家已在怀孕期间引入孕产妇百日咳疫苗接种，以保护婴儿免受感染。本研究的目的是评估母亲百日咳疫苗接种在保护婴儿免受实验室确诊的百日咳感染方面的有效性。方法。 2012 年 10 月至 2013 年 7 月期间，英格兰和威尔士进行了一项病例对照研究。病例为 10 岁以下的婴儿
Background. Infants with pertussis infection are at risk of severe clinical illness and death. Several countries, including the United Kingdom, have introduced maternal pertussis vaccination during pregnancy to protect infants from infection following national increases in pertussis notifications. The objective of this study was to estimate the effectiveness of maternal pertussis vaccination in protecting infants against laboratory-confirmed pertussis infection.Methods. A case-control study was undertaken in England and Wales between October 2012 and July 2013. Cases were infants aged