Effect of pain reduction on postural sway, proprioception, and quadriceps strength in subjects with knee osteoarthritis
Effect of pain reduction on postural sway, proprioception, and quadriceps strength in subjects with knee osteoarthritis
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DOI：
10.1136/ard.61.5.422
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发表时间：
2002-05-01
影响因子：
27.4
通讯作者：
Doherty, M
中科院分区：
文献类型：
--
作者：
Hassan, BS;Doherty, SA;Doherty, M
目的：探讨膝关节疼痛缓解对膝骨性关节炎(OA)患者股四头肌功能、本体感觉敏感度和姿势稳定性的影响。方法：采用交叉、受试者内、双盲研究设计，共纳入68例膝骨性关节炎患者。每个受试者都接受了单膝或双膝关节内注射(如果有症状)0.5%布比卡因5ml或0.9%生理盐水5ml。两周后，他们接受了替代药物的注射。受试者和观察者不知道注射的顺序，这是随机分配的。分别于注射前和注射后1h评定膝关节疼痛(100 mm视觉模拟评分)、静态姿势摆动、膝关节本体感觉敏感度、最大自主收缩(MVC)和股四头肌激活百分率。结果：布比卡因注射后1h疼痛明显减轻(平均差值为56.85，95%CI为31.01~73.65；P
Objective: To investigate whether alleviation of knee pain influences quadriceps function, proprioceptive acuity, and postural stability in patients with knee osteoarthritis (OA).Methods: A crossover, within-subject, double blind study design involving 68 subjects with painful knee OA. Each subject received an intra-articular injection into one or both knees (both if symptomatic) of either 5 ml 0.5% bupivacaine or 5 ml 0.9% saline. Two weeks later they received an injection of the alternative agent. Subjects and observer were unaware of the order of injection, which was randomly assigned. Knee pain (100 mm visual analogue scale), static postural sway, knee proprioceptive acuity, maximum voluntary contraction (MVC), and percentage activation of the quadriceps were assessed immediately before and one hour after each injection.Results: Significant pain reduction was achieved one hour post-bupivacaine (mean difference as a percentage change 56.85, 95% CI 31.01 to 73.65; p