[Development of the human fetal brain: volumetric analysis of the component parts].
[Development of the human fetal brain: volumetric analysis of the component parts].
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[人类胎儿大脑的发育：组成部分的体积分析]。
DOI：
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发表时间：
1989
期刊：
影响因子：
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通讯作者：
T. Nara
中科院分区：
文献类型：
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作者：
Y. Nakae;N. Goto;T. Nara
通过测量大脑及其组成部分(大脑皮层、皮质下白质、基底节、间脑、脑室、胚胎室周细胞层等)的体积，对人胎脑的发育进行了形态计量学评价。在妊娠期的第二个三个月。对于体积的测量，作者采用了一种独特的方法，该方法由连续火棉切片、电子图像分析仪和计算机组成。我们从体积分析的角度发现，胎儿大脑的各个组成部分都是异时发育的。在大脑的组成部分中，间脑首先发育，其次是皮质下白质和神经节，大脑皮层最后发育。结果表明，连续切片、图像分析仪和计算机分析相结合的方法是可靠和有用的，可以为脑发育的形态计量学评估提供更准确和客观的信息。
Development of human fetus brain was morphometrically evaluated through measuring volumes of the cerebrum and its component parts (i.e. cerebral cortex, subcortical white matter, basal ganglia, diencephalon, ventricles, embryonal periventricular cell layer, etc.) in the second trimester of gestational period. For the measurement of volumes, authors employed a unique method which consisted of a combination of serial celloidin sections, electric image-analyzer and computer. We found that each component part of fetus brain developed heterochronously from the view point of volumetric analyses. In the component parts of cerebrum, diencephalon developed first, followed by subcortical white matter and ganglia, and cerebral cortex developed last. It is concluded that a combined method of serial sections, image-analyzer and computer analyses is reliable and useful to obtain more precise and objective information for the morphometrical evaluation of brain development.