Opioid overdose prevention and naloxone rescue kits: what we know and what we don't know.
Opioid overdose prevention and naloxone rescue kits: what we know and what we don't know.
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DOI：
10.1186/s13722-016-0068-3
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发表时间：
2017-01-07
影响因子：
3.7
通讯作者：
Walley AY
中科院分区：
文献类型：
--
作者：
Kerensky T;Walley AY
阿片类药物使用和过量危机是持续和动态的。阿片类药物过量最初是在1990年代和2000年代由于处方阿片类药物的供应和滥用日益增加而导致的。最近，由于海洛因的广泛使用，阿片类药物过量正在以惊人的速度增加，在某些地方，海洛因与芬太尼或芬太尼衍生物混合。纳洛酮用于阿片类药物过量救援是美国卫生与公众服务部应对阿片类药物危机的三个优先领域之一。本文总结了纳洛酮的已知益处，并详细介绍了有关过量教育和纳洛酮急救包的未回答问题。希望未来的研究将解决这些知识差距，提高阿片类药物过量教育和纳洛酮分配计划的有效性，并释放纳洛酮救援包的全部承诺。
The opioid use and overdose crisis is persistent and dynamic. Opioid overdoses were initially driven in the 1990s and 2000s by the increasing availability and misuse of prescription opioids. More recently, opioid overdoses are increasing at alarming rates due to wider use of heroin, which in some places is mixed with fentanyl or fentanyl derivatives. Naloxone access for opioid overdose rescue is one of the US Department of Health and Human Services’ three priority areas for responding to the opioid crisis. This article summarizes the known benefits of naloxone access and details unanswered questions about overdose education and naloxone rescue kits. Hopefully future research will address these knowledge gaps, improve the effectiveness of opioid overdose education and naloxone distribution programs, and unlock the full promise of naloxone rescue kits.
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