Length of pseudopregnancy and pattern of uterine protein release as influenced by time and duration of oestrogen administration in the pig.
Length of pseudopregnancy and pattern of uterine protein release as influenced by time and duration of oestrogen administration in the pig.
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假妊娠的持续时间和子宫蛋白释放模式受猪雌激素施用时间和持续时间的影响。
DOI：
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发表时间：
1987
期刊：
影响因子：
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通讯作者：
B. Biggers
中科院分区：
文献类型：
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作者：
R. Geisert;M. T. Zavy;R. Wettemann;B. Biggers
在第9.5、11、12.5、14、15.5或14-16天用5 mg苯甲酸雌二醇处理后备母猪，导致发情间期约为30天。从第11天至第15天每天给予苯甲酸雌二醇或在第11天和第14天至第16天给予两个给药期，导致CL功能从给药前发情延长至60天以上。基于雌激素释放钙和子宫蛋白进入子宫腔的能力，子宫内膜对雌激素刺激的分泌反应似乎发生在发情周期的第10天之后。结果表明，维持长期CL功能似乎需要两个时期的雌激素刺激。第一个周期发生在第11天，此时子宫内膜对雌激素刺激有反应，随后在第14天后雌激素刺激的第二次延长增加。这些发现雅阁猪早期妊娠囊胚释放雌激素的正常模式。
Treatment of gilts with 5 mg oestradiol benzoate on Day 9.5, 11, 12.5, 14, 15.5 or Days 14-16 resulted in an interoestrous interval of about 30 days. Administration of oestradiol benzoate daily from Days 11 to 15 or two periods of treatment on Days 11 and 14 to 16 resulted in prolonging CL function beyond 60 days from the pre-treatment oestrus. Endometrial secretory response to oestrogen stimulation, based on the ability of oestrogen to release calcium and uterine protein into the lumen appears to occur after Day 10 of the oestrous cycle. The results suggest that maintenance of prolonged CL function appears to require two periods of oestrogen stimulation. The first period occurs on Day 11 when the endometrium has become responsive to oestrogen stimulation followed by a second prolonged increase in oestrogen stimulation after Day 14. These findings accord with the normal patterns of oestrogen released by pig blastocysts during early pregnancy.