An African horse sickness virus serotype 4 recombinant canarypox virus vaccine elicits specific cell-mediated immune responses in horses
An African horse sickness virus serotype 4 recombinant canarypox virus vaccine elicits specific cell-mediated immune responses in horses
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DOI：
10.1016/j.vetimm.2012.06.009
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发表时间：
2012-09-15
影响因子：
1.8
通讯作者：
Minke, J. M.
中科院分区：
文献类型：
--
作者：
El Garch, H.;Crafford, J. E.;Minke, J. M.
一种重组金丝雀痘病毒载体疫苗，共表达编码外衣壳蛋白的合成基因。非洲马病病毒(AHSV)4型(ALVAC(R)-AHSV4)的VP2和VP5已被证明能完全保护马匹免受强毒的同源攻击。格思里等人的研究。(2009)检测到弱的和可变的中和抗体滴度(从
A recombinant canarypox virus vectored vaccine co-expressing synthetic genes encoding outer capsid proteins. VP2 and VP5, of African horse sickness virus (AHSV) serotype 4 (ALVAC (R)-AHSV4) has been demonstrated to fully protect horses against homologous challenge with virulent field virus. Guthrie et al. (2009) detected weak and variable titres of neutralizing antibody (ranging from