Children Who Recover from Early Stunting and Children Who Are Not Stunted Demonstrate Similar Levels of Cognition
Children Who Recover from Early Stunting and Children Who Are Not Stunted Demonstrate Similar Levels of Cognition
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DOI：
10.3945/jn.109.118927
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发表时间：
2010-11-01
影响因子：
4.2
通讯作者：
Dearden, Kirk A.
中科院分区：
文献类型：
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作者：
Crookston, Benjamin T.;Penny, Mary E.;Dearden, Kirk A.
发育迟缓与儿童期和青少年期的认知发育不良、受教育年限减少、生产力下降和成年后身材矮小有关。从早期发育迟缓中恢复是可能的;然而，很少有研究探讨那些表现出线性追赶性生长的人是否会经历长期的认知缺陷。我们使用来自Young Lives研究的1674名秘鲁儿童的纵向数据，确定了与追赶性生长相关的因素，并评估了显示追赶性生长的儿童是否比在婴儿期和儿童期没有发育迟缓的儿童认知能力显著降低。根据6-18个月的儿童的人体测量数据，以及同样的儿童在4.5-6岁时的人体测量数据，我们将参与者分类为未发育不良，婴儿期发育不良但未发育不良（追赶），儿童期发育不良，以及婴儿期和儿童期发育不良。有祖父母在家里的孩子，在婴儿期发育不太严重，母亲更高的孩子更有可能在第二轮表现出追赶性生长。经历追赶性生长的儿童的词汇量和定量测试分数与未发育迟缓的儿童没有差异（分别为P = 0.6和P = 0.7）。那些在儿童期发育不良以及那些在婴儿期和儿童期发育不良的儿童在这两项评估中的得分明显低于没有发育不良的儿童。根据这项研究的结果，政策制定者和计划规划者应该考虑加倍努力，防止发育迟缓，并促进儿童在生命最初几年的追赶性生长，作为改善儿童身体和智力发展的一种方式。J.营养140：1996-2001，2010。
Stunting is associated with adverse cognitive development in childhood and adolescence, fewer years of schooling, decreased productivity, and reduced adult stature. Recovery from early stunting is possible; however, few studies explore whether those who demonstrate linear catch-up growth experience long-term cognitive deficits. Using longitudinal data on 1674 Peruvian children from the Young Lives study, we identified factors associated with catch-up growth and assessed whether children who displayed catch-up growth have significantly lower cognition than children who were not stunted during infancy and childhood. Based on anthropometric data for children 6-18 mo of age and again for the same children when they were 4.5-6 y of age, we categorized participants as not stunted, stunted in infancy but not childhood (catch-up), stunted in childhood, and stunted in infancy and childhood. Children who had grandparents in the home, had less severe stunting in infancy, and had taller mothers were more likely to demonstrate catch-up growth by round 2. Children who experienced catch-up growth had verbal vocabulary and quantitative test scores that did not differ from children who were not stunted (P = 0.6 and P = 0.7, respectively). Those stunted in childhood as well as those stunted in infancy and childhood scored significantly lower on both assessments than children who were not stunted. Based on findings from this study, policy makers and program planners should consider redoubling efforts to prevent stunting and promote catch-up growth over the first few years of life as a way of improving children's physical and intellectual development. J. Nutr. 140: 1996-2001, 2010.