Inhibitory control task is decreased in vascular incontinence patients
Inhibitory control task is decreased in vascular incontinence patients
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DOI：
10.1007/s10286-013-0187-9
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发表时间：
2013-04-01
影响因子：
5.8
通讯作者：
Yamamoto, Tatsuya
中科院分区：
文献类型：
--
作者：
Haruta, Hiroyuki;Sakakibara, Ryuji;Yamamoto, Tatsuya
“血管性失禁”是由于脑白质变化（WMC）导致的老年人失禁的一部分。我们研究了血管性失禁患者的几种认知任务表现与尿动力学逼尿肌过度活动 (DO) 之间的关系。我们招募了 40 名因 WMC 而出现下尿路症状的患者 [20 名男性，20 名女性；20 名男性，20 名女性；平均年龄 77 岁（60-89 岁）]。排除 LUT 功能障碍的其他神经系统、泌尿系统和全身原因。所有患者均接受尿动力学测试和两组认知任务，即简易精神状态检查（MMSE）（一般认知任务）和额叶评估电池（FAB）（额叶任务）。最常见的泌尿症状是尿急（27名患者），其次是尿失禁（26名患者）和夜间尿频（25名患者）。尿动力学测试显示 22 名患者存在 DO。认知测试显示，患者的平均 MMSE 评分为 25.8（范围 15-30），平均 FAB 评分为 13.6（4-18）。 DO 与 MMSE 或 FAB 总分之间没有关系，但我们对 DO 与 FAB 的六个子域（概念化、心理灵活性、编程、干扰敏感性、抑制控制和环境自主性）之间关系的分析揭示了 DO 与抑制控制任务之间存在显着关系 (p < 0.005)。 本研究结果表明，血管失禁患者的 DO 抑制控制任务表现下降。
'Vascular incontinence' is a part of elderly incontinence due to cerebral white matter change (WMC). We studied the relationship between performance on several cognitive tasks and urodynamic detrusor overactivity (DO) in patients with vascular incontinence.We recruited 40 patients with lower urinary tract symptoms due to WMC [20 male, 20 female; mean age 77 years (60-89 years)]. Other neurologic, urologic, and systemic causes of LUT dysfunction were excluded. All patients underwent urodynamics tests and two sets of cognitive tasks, i.e., the Mini-Mental State Examination (MMSE) (general cognitive tasks), and the Frontal Assessment Battery (FAB) (frontal lobe tasks).The most common urinary symptom was urinary urgency (27 patients), followed by urinary incontinence (26) and nocturnal urinary frequency (25). The urodynamic testing revealed DO in 22 patients. The cognitive testing revealed that the patients' mean MMSE score was 25.8 (range 15-30), and their mean FAB score was 13.6 (4-18). There was no relationship between DO and the total MMSE or FAB score, but our analysis of the relationship between DO and the six subdomains of the FAB (conceptualization, mental flexibility, programming, sensitivity to interference, inhibitory control, and environmental autonomy) revealed a significant relationship between DO and the inhibitory control task (p < 0.005).The results of the present study showed that performance on an inhibitory control task is decreased in vascular incontinence patients with DO.