FAMILIAL VESICOURETERAL REFLUX - A PROSPECTIVE-STUDY

FAMILIAL VESICOURETERAL REFLUX - A PROSPECTIVE-STUDY
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DOI:
10.1016/s0022-5347(17)53184-5
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发表时间:
1982-01-01
期刊:
影响因子:
6.6
通讯作者:
NOE, HN
NOE, HN
中科院分区:
医学1区
文献类型:
--
作者:
JERKINS, GR;NOE, HN

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建立了一项前瞻性研究,以确定反流患者的兄弟姐妹[儿童]中膀胱输尿管反流的发生率。78例反流104兄弟姐妹进行了筛选与清醒排尿膀胱造影和34(32%)被发现有反流。在这34名同胞中,25名(73%)没有异常排尿症状或尿路感染史。反流发生率最高的是那些有肾瘢痕影像学证据的患者的兄弟姐妹。早期发现和随访,在这个高风险的群体可能是一个重要的工具,以确定更多的膀胱输尿管反流的自然史及其与肾损害的关系。
A prospective study was established to identify the incidence of vesicoureteral reflux in the siblings [children] of patients with reflux. Of 78 patients with reflux 104 siblings were screened with an awake voiding cystogram and 34 (32%) were found to have reflux. Of these 34 siblings 25 (73%) had no abnormal voiding symptoms or history of urinary tract infection. The highest incidence of reflux was found in the siblings of those patients with radiographic evidence of renal scarring. Early detection and followup in this high risk group may be a vital tool in determining more about the natural history of vesicoureteral reflux and its relationship to renal damage.