Three-dimensional matrixlike focusing of microparticles in flow through minichannel using acoustic standing waves: An experimental and modeling study

Three-dimensional matrixlike focusing of microparticles in flow through minichannel using acoustic standing waves: An experimental and modeling study
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DOI:
10.1250/ast.37.221
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发表时间:
2016-09
影响因子:
0.7
通讯作者:
C. Perfetti;C. Iorio
C. Perfetti;C. Iorio
中科院分区:
--
文献类型:
--
作者:
C. Perfetti;C. Iorio

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在这项工作中,我们证明了使用体声波驻波聚焦微粒流以产生矩阵状分布的可能性。为了实现这一目标,轴向声激励上进行的球形准单分散微粒的悬浮液中的流动通过微通道与平方米的横截面为2 mm-2 mm。该对换能器元件还用于在对应于其理论本征模式的几个频率下进行刺激。通过与正方形几何形状相关联的声辐射力的反射来实现聚焦颗粒的矩阵状三维(3D)结构的生成。通过干涉数字全息显微镜记录颗粒位置,并针对每个实验设置计算横截面中相应的归一化分布。聚焦效率的变化通过施加到压电部件的电压和喷射流量引起的声能密度的变化进行了研究。声场进行了数值计算,并与实验的粒子在通道的横截面的位置进行了比较。
In this work, we demonstrate the possibility of focusing a stream of microparticles to generate a matrixlike distribution using bulk acoustic standing waves. To achieve this goal, an axial acoustic excitation was performed on a suspension of spherical quasi-monodisperse microparticles in a flow through minichannel with a square cross section of 2mm 2mm. The pair of transducer elements was also used for stimulation at several frequencies corresponding to its theoretical eigenmodes. The generation of the matrixlike tree-dimensional (3D) structures of focused particles was achieved by reflections of the acoustic radiation force associated with the square geometry. Particle positions were recorded by interferometric digital holographic microscopy, and the corresponding normalized distribution in the cross section was calculated for each experimental setting. The focusing efficiency was investigated through the variation of the acoustic energy density induced by the voltage applied to the piezo part and the injected flow rate. The acoustic field was numerically computed and compared with the experimental positions of particles in the cross section of the channel.