A 12-year follow-up study of psychiatric symptomatology among cocaine-dependent men
A 12-year follow-up study of psychiatric symptomatology among cocaine-dependent men
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DOI：
10.1016/j.addbeh.2006.01.013
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发表时间：
2006-11-01
影响因子：
4.4
通讯作者：
Paredes, Alfonso
中科院分区：
文献类型：
--
作者：
Herbeck, Diane M.;Hser, Yih-Ing;Paredes, Alfonso
This prospective longitudinal study examines patterns of psychiatric symptomatology among men admitted to treatment for cocaine dependence in 1988-1989. Study participants were interviewed at treatment intake, and at 1 year, 2 years and 12 years after treatment. The Hopkins Symptom Checklist-58 (SCL) and Natural History Interview were administered at the 4 time points. Of the 266 study participants interviewed at the 12-year follow-up, 138 (52%) had been cocaine abstinent for 5 years or more. Repeated measures ANOVA assessed changes in SCL scores over time for cocaine-abstinent and non-abstinent men. Both groups had similarly high mean SCL scores at treatment intake, and reductions in symptom severity I year after treatment. By 12-year follow-up, the abstinent group reported significantly lower SCL scores than the non-abstinent group on 4 of the 5 symptom measures. Additionally, cocaine-abstinent men reported lower rates of depressive and psychotic disorders, and lower use of psychopharmacologic and inpatient treatment than non-abstinent men. These findings suggest that severe psychiatric symptomatology persists among individuals unable to achieve a stable recovery from cocaine dependence. (c) 2006 Elsevier Ltd. All rights reserved.
