Cytokine-containing liposomes as adjuvants for subunit vaccines.
Cytokine-containing liposomes as adjuvants for subunit vaccines.
复制标题
含有细胞因子的脂质体作为亚单位疫苗的佐剂。
DOI:
10.1007/978-1-4615-1823-5_29
复制
发表时间:
1995
期刊:
影响因子:
--
通讯作者:
Cleland,JL
中科院分区:
文献类型:
--
作者:
Lachman,LB;Shih,LC;Rao,XM;Ullrich,SE;Cleland,JL
Liposomes provide a carrier function to bring antigen to cells of the immune system and to provide a mechanism for slow release of antigen. Since liposomes are slowly absorbed, they also provide a “depot effect” in which the presence of the antigen may be maintained for a longer period of time compared to soluble antigen (Alving, 1991). In addition to antigen, liposomes may carry other agents that potentiate an immune response. In this chapter we will present our current data concerning the adjuvant effect of a special type of liposomes containing a subunit protein antigen and cytokines.