Walking in the Light: How History of Physical Activity, Sunlight, and Vitamin D Account for Body Fat-A UK Biobank Study.
Walking in the Light: How History of Physical Activity, Sunlight, and Vitamin D Account for Body Fat-A UK Biobank Study.
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DOI：
10.1002/oby.22852
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发表时间：
2020-08
期刊：
影响因子：
--
通讯作者：
Willette AA
中科院分区：
文献类型：
--
作者：
Klinedinst BS;Meier NF;Larsen B;Wang Y;Yu S;Mochel JP;Le S;Wolf T;Pollpeter A;Pappas C;Wang Q;Allenspach K;Wang L;Russell D;Bennett DA;Willette AA
High prevalence of vitamin D deficiency and obesity drive the need for successful strategies that elevate vitamin D levels, prevent adipogenesis and stimulate lipolysis. We provide a theoretical model to evaluate how physical activity and sunlight exposure influence serum vitamin D levels and regional adiposity. We hypothesized posteriori that sunlight is associated with undifferentiated visceral adiposity by increasing the ratio of brown to white adipose tissue. Using ten-year longitudinal data, accelerometry, a sun exposure questionnaire, and regional adiposity quantified by DEXA imaging, a structural equation mediation model of growth curves was constructed with data-driven methodology. Sunlight and physical activity conjointly increased serum vitamin D. Changes in vitamin D levels partially mediated how sunlight and physical activity impacted adiposity in visceral and subcutaneous regions within a subjective physical activity model. In an objective physical activity model, vitamin D was a mediator for subcutaneous regions only. Interestingly, sunlight was associated with less adiposity in subcutaneous regions, yet greater adiposity in visceral regions. Sunlight and physical activity may increase vitamin D levels. For the first time, we characterize a positive association between sunlight and visceral adiposity. Further investigation and experimentation are necessary to clarify the physiological role of sunlight exposure on adipose tissue.
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DOI：
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发表时间：
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影响因子：
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