Modification of Hydroxybenzopyranoids: Facile Deoxygenation of 2,2-Dimethyl-7-hydroxy-4-chromanones and a New Approach to Their Novel Mercapto Analogs
Modification of Hydroxybenzopyranoids: Facile Deoxygenation of 2,2-Dimethyl-7-hydroxy-4-chromanones and a New Approach to Their Novel Mercapto Analogs
复制标题
羟基苯并吡喃类化合物的修饰：2,2-二甲基-7-羟基-4-色满酮的轻松脱氧及其新型巯基类似物的新方法
DOI：
10.1021/jo00100a038
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发表时间：
1994
影响因子：
3.6
通讯作者：
T. Patonay
中科院分区：
文献类型：
--
作者：
P. Sebők;T. Timár,;T. Eszenyi,;T. Patonay
本文报道了一系列取代的2,2 -二甲基-7-羟基-4-甾酮通过其磺酸盐、异脲和硫代氨基甲酸酯衍生物容易脱氧。通过对相应的硫氨基甲酸酯进行水解，合成了新型2,2 -二甲基-7-巯基-4-激素。在这些羟基苯并吡喃类化合物的情况下，不同的脱氧程序的范围和局限性也提出。
A facile deoxygenation of a systematic series of substituted 2, 2-dimethyl-7-hydroxy-4-chromanones via their sulfonate, isourea, and thiocarbamate derivatives is reported. The synthesis of novel 2, 2-dimethyl-7-mercapto-4-chromanones has been accomplished by the hydrolysis of the correspond-ing thiocarbamates. The scope and limitations of different deoxygenation procedures in the case of these hydroxybenzopyranoids are also presented.