Blood vessels of the glaucomatous optic disc in experimental primate and human eyes.
Blood vessels of the glaucomatous optic disc in experimental primate and human eyes.
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DOI：
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发表时间：
1984-08
影响因子：
4.4
通讯作者：
H. Quigley;R. Hohman;E. M. Addicks;W. Green
中科院分区：
文献类型：
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作者：
H. Quigley;R. Hohman;E. M. Addicks;W. Green
实验慢性青光眼灵长类动物的眼睛和定量测量的毛细血管面积的视神经乳头。尽管椎间盘组织随着神经瘤的进展而大量丢失，但毛细血管占据的神经头百分比保持正常。这一发现与单纯性视神经萎缩相同，表明尽管有大量的组织损失，神经头仍能保持稳定的毛细血管与组织的比例。对人青光眼眼睛的进一步观察证实，没有选择性地更大的毛细血管体积损失与视神经头的神经组织损失不成比例。灵长类动物和人类青光眼眼的血管造影显示，当巩膜筛板前有很少或没有剩余的神经或血管组织时，最常发生椎间盘血管外观的变化。
Experimental chronic glaucoma was produced in primate eyes and quantitative measurements were made of the capillary area in the optic nerve head. The percent of the nerve head occupied by capillaries remained normal despite considerable loss of disc tissue as glaucomatous excavation proceeded. This finding, identical to that in simple optic atrophy, suggests that the nerve head can maintain a stable capillary to tissue ratio despite substantial tissue loss. Further observations on human glaucoma eyes confirmed that there is not selectively greater loss of capillary volume out of proportion to the loss of neural tissue of the optic nerve head. Fluorescein angiography of primate and human glaucoma eyes showed that a change in the appearance of disc vessels occurred most frequently when there was little or no remaining neural or vascular tissue anterior to the scleral lamina cribrosa.