Association Between the Rh Blood Group and the Covid-19 Susceptibility
Association Between the Rh Blood Group and the Covid-19 Susceptibility
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DOI：
10.4999/uhod.204247
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发表时间：
2020-01-01
影响因子：
0.6
通讯作者：
Demir, Cengiz
中科院分区：
文献类型：
--
作者：
Arac, Esref;Solmaz, Ihsan;Demir, Cengiz
我们的目的是调查具有ABO和Rh血型系统的新冠肺炎是否有易感性。本研究采用医院信息管理系统提供的数据，对3月16日至5月20日期间因新冠肺炎流行而住院的患者进行了回顾性调查。以2019年在我省对127091人进行的血型研究数据作为对照组。在我们的研究中，被诊断为新冠肺炎的患者的A型血显著增加，而B型、AB型和O型血则明显减少。但统计分析显示，新冠肺炎患者与健康人之间的ABO血型系统并无显著差异。当按Rh血型系统分析时，发现新冠肺炎患者的Rh阳性率显著高于对照组(p=0.000)。我们的研究表明，Rh(-)血型具有保护性，而Rh(+)血型更容易感染Covid19。我们认为这是有价值的，因为这是我国第一次揭示新冠肺炎与血型关系的研究，也是世界文献中唯一揭示新冠肺炎与Rh(+)关系的研究。
We aimed to investigate whether there is a predisposition to COVID-19 with ABO and Rh blood group systems. This study was a retrospective study that investigate the patients admitted to our hospital between March 16 -May 20 due to Covid-19 pandemic and conducted with data revealed from the hospital Information Management System A total of 392 patients were included in this study, including 227 PCR test positive patients with blood group information in the system and 165 possible patients with CT findings in favor of Covid-19. Data from a blood group study conducted with 127091 people in our province in 2019 were used as a control group. In our study, a significant increase was observed in the blood group A in patients diagnosed with Covid-19, and a decrease was found in the blood groups B, AB and especially O. However, statistical analysis showed no significant difference between Covid-19 patients and healthy individuals in terms of ABO blood group system. When analyzed in terms of Rh blood group system, it was found that Rh positivity was statistically significantly higher in patients with Covid-19 (p= 0.000). Our study suggests that the Rh (-) blood group is protective and the Rh (+) blood group is predisposed to Covid 19 significantly. We think that it is valuable because it is the first study to reveal the relationship between Covid-19 and blood type in our country and the only one to reveal the relationship between Covid-19 and Rh (+) in the world literature.