EXPERIMENTAL STUDIES ON TICK TRANSMISSION OF TULAREMIA ORGANISMS
EXPERIMENTAL STUDIES ON TICK TRANSMISSION OF TULAREMIA ORGANISMS
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DOI：
10.1093/oxfordjournals.aje.a119585
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发表时间：
1953-01-01
影响因子：
--
通讯作者：
HOPLA, CE
中科院分区：
文献类型：
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作者：
HOPLA, CE
采用定量研究方法，试图观察美洲钝眼蜱体内发生的变化。在长时间的饥饿和以各种宿主为食之后。该蜱在长时间禁食后保留了土拉热杆菌，然而，每只蜱的土拉菌微生物数量随着喂食后时间的增加而减少。喂养感染的A.在各种恢复的和抗性的动物中，没有观察到感染百分比的变化，也没有观察到生物体数量的减少。相反，观察到每只蜱虫的微生物数量有一定程度的增加。LD50滴定表明蜱虫传代后兔热病微生物的毒力略有损失。
Quantitative methods of study were used in an attempt to observe the changes which took place within Amblyomma americanum. after pro-longed periods of starvation and after feeding on various hosts. This tick retained Bacterium tularense after prolonged periods of fasting, however, the number of tularemia organisms per tick decreased as the length of time after feeding increased. In feeding infected A. americanum upon various recovered and resistant animals no change in the percentage infected was observed, nor was a decrease in the number of organisms noted. On the contrary, a certain amount of increase in the number of organisms per tick was observed. The LD50 titration indicated a slight loss of virulence in the tularemia organ-isms upon tick passage.