Existing data sources for clinical epidemiology: Aarhus University Prescription Database.
Existing data sources for clinical epidemiology: Aarhus University Prescription Database.
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DOI：
10.2147/clep.s13458
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发表时间：
2010-12-02
影响因子：
3.9
通讯作者：
Pedersen, Lars
中科院分区：
文献类型：
--
作者：
Ehrenstein, Vera;Antonsen, Sussie;Pedersen, Lars
北欧国家以人口为基础的处方数据库已成为流行病学研究的支柱。丹麦拥有国家和区域人口处方数据库。奥胡斯大学处方数据库收集了北丹麦地区和丹麦中部地区所有社区药房发放的报销药物的数据。这些地区总共有180万居民，占丹麦人口的三分之一。丹麦的初级卫生保健部门，包括全科医生、专家和牙医，产生了约96%的处方销售，其中大部分是可报销的，由社区药房配发。奥胡斯大学处方数据库将该地区的药房记录合并在一个数据库中，并为研究目的进行维护和更新。每个分配记录包含患者、药物和处方相关的数据。配药记录保留了病人的通用个人标识符，允许个人层面与所有丹麦登记和医疗数据库建立联系。关联数据在临床流行病学中有许多应用，包括药物利用研究、安全监测、病因学研究和验证研究。
Population-based prescription databases in Nordic countries have become a mainstay of epidemiologic research. Denmark has both national and regional population-based prescription databases. Aarhus University Prescription Database collects data on reimbursed medications dispensed at all community pharmacies of the North Denmark Region and the Central Denmark Region. The regions have a combined population of 1.8 million inhabitants, or one-third of the Danish population. Denmark's primary health care sector, which includes general practitioners, specialists, and dentists, generates about 96% of the prescription sales, most of which are reimbursable and are dispensed by the community pharmacies. The Aarhus University Prescription Database combines the region's pharmacy records in a single database, maintained and updated for research purposes. Each dispensation record contains patient-, drug-, and prescriber-related data. Dispensation records retain patients' universal personal identifier, which allows for individual-level linkage to all Danish registries and medical databases. The linked data have many applications in clinical epidemiology, including drug utilization studies, safety monitoring, etiologic research, and validation studies.