Lymphocyte To High-Density Lipoprotein Ratio As A New Indicator Of Inflammation And Metabolic Syndrome
Lymphocyte To High-Density Lipoprotein Ratio As A New Indicator Of Inflammation And Metabolic Syndrome
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DOI：
10.2147/dmso.s219363
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发表时间：
2019-01-01
期刊：
影响因子：
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通讯作者：
Zou, Hequn
中科院分区：
文献类型：
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作者：
Chen, Haishan;Xiong, Chongxiang;Zou, Hequn
目的：代谢综合征是一种慢性低度炎症状态，是一个全球性的公共卫生问题。这项研究观察了中国南方沿海城市患有和不患有代谢综合征的受试者的血液学参数的变化以及淋巴细胞与高密度脂蛋白胆固醇(HDLC)比值(LHR)作为一项新的指标的预测价值。结果：METS与白细胞计数、淋巴细胞总数、中性粒细胞计数、红细胞计数、红细胞压积、血红蛋白、超敏C反应蛋白水平呈正相关(P<0.05)。
Purpose: Metabolic syndrome (MetS), which is a global public health problem, is a state of chronic low-grade inflammation. This study looked at the changes in hematological parameters and the predictive value of the lymphocyte to high-density lipoprotein cholesterol (HDL-C) ratio (LHR) as a new index in subjects with and without MetS in coastal cities in southern China.Patients and methods: In this cross-sectional study, there were 852 participants (n = 598 with MetS and n = 254 without MetS). MetS was defined in accordance with the National Cholesterol Education Program, Adult Treatment Panel III (NCEP-ATP III) criteria.Results: MetS was positively correlated with white blood cell count, total lymphocyte count, neutrophil count, red blood cell count, hematocrit, hemoglobin, and high-sensitivity C-reactive protein levels (p