PATHWAYS CONDUCTING AMYGDALOID INFLUENCE ON FEMININE SEXUAL-BEHAVIOR IN THE RAT
PATHWAYS CONDUCTING AMYGDALOID INFLUENCE ON FEMININE SEXUAL-BEHAVIOR IN THE RAT
复制标题
DOI：
10.1016/0166-4328(84)90212-2
复制
发表时间：
1984-01-01
影响因子：
2.7
通讯作者：
CARRER, HF
中科院分区：
文献类型：
--
作者：
MASCO, DH;CARRER, HF
在用苯甲酸雌二醇和黄体酮引发的卵巢切除雌性大鼠中，对内侧杏仁核前部（AMEa）进行电化学刺激，增加脊柱前凸频率，但在横断终纹（ST）或腹侧杏仁离通路（VAF）的大鼠中未发现这种效应。刺激外侧杏仁核（ALp）后部后观察到的前凸频率降低，在横断 VAF 的动物中持续存在，但在横断 ST 的动物中消失。还研究了横切这些通路对多单位的影响，并通过刺激两个杏仁核在下丘脑腹内侧核（VMN）中诱发反应。 ST 或 VAF 损伤后，AMEa 刺激引起的反应较小或消失，但 ALp 刺激引起的反应仅受 ST 损伤影响。显然，ST 进行源自 AMEa 和 ALp 的活动，以互补的方式影响性接受性，而 VAF 包含源自 AMEa 的纤维，其激活会增加接受性。这些行为效应可能是 VMN 神经元活动调节作用的结果。
In ovariectomized female rats primed with estradiol benzoate and progesterone, electrochemical stimulation of medial amygdaloid nucleus, anterior part (AMEa), increased lordotic frequency, but this effect was not found in rats with transection of the stria terminalis (ST) or the ventral amygdalofugal pathways (VAF). The decrease in lordotic frequency observed after stimulation of the posterior part of the lateral amygdaloid nucleus (ALp), persisted in animals with transection of the VAF, but was eliminated in animals with section of the ST. The effect of transecting these pathways on the multiunit and held responses evoked in the hypothalamic ventromedial nucleus (VMN) by stimulation of both amygdaloid nuclei was also studied. Responses evoked by AMEa stimulation were smaller or disappeared after lesion of either the ST or the VAF, but responses evoked by ALp stimulation were affected by lesion of the ST only. Evidently, the ST conducts activity originating in AMEa and ALp which affects sexual receptivity in a complementary fashion, whereas VAF contains AMEa originated fibers whose activation increase receptivity. These behavioral effects may be the consequence of modulatory action on VMN neuronal activity.