Efficacy and safety of balloon-occluded retrograde transvenous obliteration of gastric varices with lauromacrogol foam sclerotherapy: initial experience
Efficacy and safety of balloon-occluded retrograde transvenous obliteration of gastric varices with lauromacrogol foam sclerotherapy: initial experience
复制标题
聚桂醇泡沫硬化剂球囊闭塞逆行经静脉闭塞胃静脉曲张的疗效和安全性：初步经验
DOI：
10.1007/s00261-017-1346-6
复制
发表时间：
2018
影响因子：
2.4
通讯作者：
Yang Li
中科院分区：
文献类型：
--
作者：
Luo Xuefeng;Ma Huaiyuan;Yu Jiaze;Zhao Ying;Wang Xiaoze;Yang Li
目的经静脉逆行闭塞术（BRTO）是治疗胃静脉曲张的一种广泛接受的方法。本研究的目的是评估BRTO的有效性和安全性与聚月桂醇泡沫sclerotherapy.Materials和MethodsBetween 2014年5月和2015年6月，32例患者进行了治疗与聚月桂醇泡沫。聚桂醇泡沫使用多种试剂的组合制成，室内空气：聚桂醇：造影剂的比例为2：1：1。使用对比增强计算机断层扫描（CT）和endoscopy.ResultsTechnical成功32例（96.9%）中的31例。2例患者发生门静脉血栓形成，并自行消退。未观察到其他严重并发症。所用聚月桂醇的总体平均剂量为12.4 mL（范围，8-20 mL）。在随访CT中，所有31例患者（100%）均证实了GV完全闭塞。31例患者中有7例（22.6%）发生食管静脉曲张恶化。3例患者发生食管静脉曲张破裂，采用套扎成功治疗。5例患者（16.1%）的腹水恶化，反应良好，利尿therapy.ConclusionBRTO利用聚月桂醇泡沫似乎是一个安全和有用的治疗方案，在GVs患者在短期内。
PurposeBalloon-occluded retrograde transvenous obliteration (BRTO) is a widely-accepted treatment for gastric varices (GVs). The purpose of this study was to evaluate the efficacy and safety of BRTO with lauromacrogol foam sclerotherapy.Materials and methodsBetween May 2014 and June 2015, 32 patients were treated with lauromacrogol foam. Lauromacrogol foam was made using a combination of agents, with a 2:1:1 ratio of room air: lauromacrogol: contrast media. Patients were followed up using contrast-enhanced computed tomography (CT) and endoscopy.ResultsTechnical success was achieved in 31 of 32 patients (96.9%). Portal vein thrombosis occurred in two patients and resolved spontaneously. No other major complications were observed. The overall mean dose of lauromacrogol used was 12.4 mL (range, 8–20 mL). Complete obliteration of GVs was confirmed in all 31 patients (100%) on follow-up CT. Seven of the 31 patients (22.6%) experienced worsening of esophageal varices. Rupture of esophageal varices occurred in three patients and was treated successfully with band ligation. Five patients (16.1%) experienced worsening of ascites and responded well to diuretic therapy.ConclusionBRTO utilizing lauromacrogol foam appears to be a safe and useful treatment option in patients with GVs in the short term.