An efficient way for the N-formylation of amines by inorganic-ligand supported iron catalysis
An efficient way for the N-formylation of amines by inorganic-ligand supported iron catalysis
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DOI：
10.1039/c9gc03564h
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发表时间：
2020-02
期刊：
影响因子：
9.8
通讯作者：
Zhikang Wu;Yongyan Zhai;Wenshu Zhao;Zheyu Wei;Han Yu;Sheng Han;Yongge Wei
中科院分区：
文献类型：
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作者：
Zhikang Wu;Yongyan Zhai;Wenshu Zhao;Zheyu Wei;Han Yu;Sheng Han;Yongge Wei
报道了无机配体负载的铁（III）催化的甲酸和胺偶联形成甲酰胺的第一个实例。纯无机催化剂（NH 4）3[FeMo 6 O 18（OH）6]（1）由中心FeIII单原子核支撑在由六个MoVIO 6八面体组成的环状无机配体内组成，显示出优异的活性和选择性，并且避免了使用复杂/商业上不可得的有机配体。在温和的条件下，成功地将各种伯胺和仲胺转化为相应的甲酰胺，并首次实现了伯二胺的合成。Fe催化剂1可以重复使用几次而没有明显的活性损失。
The first example of an inorganic-ligand supported iron(III) catalysed coupling of formic acid and amines to form formamides is reported. The pure inorganic catalyst (NH4)3[FeMo6O18(OH)6] (1), which consists of a central FeIII single-atomic core supported within a cycle-shaped inorganic ligand consisting of six MoVIO6 octahedra, shows excellent activity and selectivity, and avoids the use of complicated/commercially unavailable organic ligands. Various primary amines and secondary amines have been successfully transformed into the corresponding formamides under mild conditions, and the formylation of primary diamines has also been achieved for the first time. The Fe catalyst 1 can be reused several times without appreciable loss of activity.