The Cat That Caught the Canary: What To Do with Single-Molecule Trapping

The Cat That Caught the Canary: What To Do with Single-Molecule Trapping
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DOI:
10.1021/nn202313g
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发表时间:
2011-07-01
期刊:
影响因子:
17.1
通讯作者:
Fields, Alexander P.
Fields, Alexander P.
中科院分区:
材料科学1区
文献类型:
--
作者:
Cohen, Adam E.;Fields, Alexander P.

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最近,通过使用实时跟踪和主动反馈来抑制布朗运动,可以在水溶液中捕获单个荧光生物分子。我们提出的调查领域中,反布朗电动力学(ABEL)捕获的单分子可能会导致重大的新见解生物分子动力学。
It has recently become possible to trap individual fluorescent biomolecules in aqueous solution by using real-time tracking and active feedback to suppress Brownian motion. We propose areas of investigation In which anti-Brownian electrokinetic (ABEL) trapping of single molecules is likely to lead to significant new insights into biomolecular dynamics.