Ictal high-frequency oscillations at 80-200 Hz coupled with delta phase in epileptic spasms
Ictal high-frequency oscillations at 80-200 Hz coupled with delta phase in epileptic spasms
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DOI：
10.1111/j.1528-1167.2011.03263.x
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发表时间：
2011-10-01
期刊：
影响因子：
5.6
通讯作者：
Asano, Eishi
中科院分区：
文献类型：
--
作者：
Nariai, Hiroki;Matsuzaki, Naoyuki;Asano, Eishi
先前对癫痫痉挛的研究报告称，发作事件与涉及广泛区域的高频振荡（HFO）或δ波有关。我们确定了 80-200 Hz 的发作期 HFO 是否与慢波相位耦合，发作期慢波是否是弥散同步信号或局部同步信号，以及 HFO 与慢波相位之间的耦合模式在发作状态和发作间期状态之间是否不同。我们研究了 11 名接受术外皮质电图 (ECoG) 记录的儿童。在癫痫发作部位的发作期和发作间期 HFO 峰值处测量慢波的相位和幅度。发作期 HFO 被紧紧锁定在慢波相位
Previous studies of epileptic spasms reported that ictal events were associated with high-frequency oscillations (HFOs) or delta waves involving widespread regions. We determined whether ictal HFOs at 80-200 Hz were coupled with a phase of slow-wave, whether ictal slow-waves were diffusely or locally synchronous signals, and whether the mode of coupling between HFOs and slow-wave phases differed between ictal and interictal states. We studied 11 children who underwent extraoperative electrocorticography (ECoG) recording. The phases and amplitudes of slow-waves were measured at the peak of ictal and interictal HFOs in the seizure-onset sites. Ictal HFOs were locked tightly to the phase of slow-wave at