Relationship between insomnia and depression in a community sample depends on habitual sleep duration.
Relationship between insomnia and depression in a community sample depends on habitual sleep duration.
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DOI：
10.1007/s41105-020-00255-z
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发表时间：
2020-04
影响因子：
1.1
通讯作者：
Grandner MA
中科院分区：
文献类型：
--
作者：
Tubbs AS;Gallagher R;Perlis ML;Hale L;Branas C;Barrett M;Gehrels JA;Alfonso-Miller P;Grandner MA
睡眠障碍，如睡眠时间短和失眠，是抑郁症的核心特征。然而，目前还不清楚睡眠时间和失眠是否对抑郁严重程度或个别症状有交互影响。数据来自一个社区样本(N=1007)，其中包含对失眠严重程度指数、患者健康问卷9(PHQ-9)和平均睡眠时间的回答。回归分析根据失眠严重程度和睡眠时间确定抑郁症状的流行风险(PR)。抑郁程度与失眠严重程度(PR1.09，p<；0.001)和睡眠时间短(PR1.52，p<；0.001)相关，但两者之间的交互作用是负的(PR0.97，p<；0.001)。睡眠时间增加了食欲失调(PR1.86，p<；0.001)、疲劳(PR1.51，p<；0.001)、注意力难以集中(PR1.61，p=0.003)、失败感(PR1.58，p=0.002)和自杀行为(PR2.54，p=0.01)的流行风险。睡眠时间与失眠呈负交互作用，在3%~6%之间。在临床显著抑郁症(PHQ和GT；=10)中，只有失眠严重程度增加抑郁严重程度的流行风险(PR1.02，p=0.001)。失眠和睡眠不足预示着抑郁症的流行，但它们的交互作用是负面的。因此，虽然失眠与抑郁的严重程度和症状有更大的关联，但这种关联依赖于习惯性睡眠时间。
Sleep disturbances, such as short sleep duration and insomnia, are core features of depression. However, it is unclear if sleep duration and insomnia have an interactive effect on depression severity or individual symptoms. Data were drawn from a community sample (N = 1007) containing responses on the Insomnia Severity Index, Patient Health Questionnaire–9 (PHQ-9), and average sleep duration. Regression analyses determined the prevalence risks (PR) of symptoms of depression based on insomnia severity and sleep duration. Depression severity was related to insomnia severity (PR 1.09, p < 0.001) and short sleep duration (PR 1.52, p < 0.001), but the interaction between the two was negative (PR 0.97, p < 0.001). Insomnia severity increased the prevalence risk of all individual depression symptoms between 8 and 15%, while sleep duration increased the prevalence risk of appetite dysregulation (PR 1.86, p < 0.001), fatigue (PR 1.51, p < 0.001), difficulty concentrating (PR 1.61, p = 0.003), feelings of failure (PR 1.58, p = 0.002), and suicidal behavior (PR 2.54, p = 0.01). The interaction of sleep duration and insomnia was negative and ranged between 3 and 6%. In clinically significant depression (PHQ >=10), only insomnia severity increased the prevalence risk of depression severity (PR 1.02, p = 0.001). Insomnia and short sleep predict prevalent depression, but their interactive effect was negative. Thus, while insomnia had a greater association with depression severity and symptoms, this association was dependent on habitual sleep duration.
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影响因子：
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