Influenza vaccination of health care workers in long-term-care hospitals reduces the mortality of elderly patients
Influenza vaccination of health care workers in long-term-care hospitals reduces the mortality of elderly patients
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DOI：
10.1093/infdis/175.1.1
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发表时间：
1997-01-01
影响因子：
6.4
通讯作者：
Carman, WF
中科院分区：
文献类型：
--
作者：
Potter, J;Stott, DJ;Carman, WF
建议将卫生保健工作者（HCW）接种疫苗作为长期护理老年患者预防流感的策略，但尚未有对照研究表明这种方法是否有效。在1994-1995年冬季，1059例患者在12个老年医疗长期护理点，随机接种HCWs，进行了研究。在为医务工作者提供疫苗接种的医院中，1078名医务工作者中有653名（61%）接受了疫苗接种，医务工作者的疫苗接种与总患者死亡率从17%降至10%相关（比值比[OR]，0.56; 95%置信区间[CI]，0.40-0.80）和流感样疾病（OR，0.57; 95% CI，0.34-0.94）。患者接种疫苗对死亡率无显著影响（OR，1.15; 95%CI，0.81-1.64）。这项研究的结果支持建议接种流感疫苗的医护人员在长期的老年护理。对年老体弱的长期护理患者接种疫苗可能不会带来临床上值得的益处。
Vaccination of health care workers (HCWs) is recommended as a strategy for preventing influenza in elderly patients in long-term care, However, there have been no controlled studies to show whether this approach is effective. During the winter of 1994-1995, 1059 patients in 12 geriatric medical long-term-care sites, randomized for vaccination of HCWs, were studied. In hospitals where HCWs were offered vaccination, 653 (61%) of 1078 were vaccinated, Vaccination of HCWs was associated with reductions in total patient mortality from 17% to 10% (odds ratio [OR], 0.56; 95% confidence interval [CI], 0.40-0.80) and in influenza-like illness (OR, 0.57; 95% CI, 0.34-0.94). Vaccination of patients was not associated with significant effects on mortality (OR, 1.15; 95% CI, 0.81-1.64). Results of this study support recommendations for vaccination against influenza of HCWs in longterm geriatric care. Vaccination of frail elderly long-term-care patients may not give clinically worthwhile benefits.