Marijuana and host resistance to herpesvirus infection.

Marijuana and host resistance to herpesvirus infection.
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大麻和宿主对疱疹病毒感染的抵抗力。

DOI:
10.1007/978-1-4615-2980-4_14
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发表时间:
1993
影响因子:
--
通讯作者:
Fischer-Stenger,K
Fischer-Stenger,K
中科院分区:
医学4区
文献类型:
--
作者:
Cabral,GA;Pettit,DA;Fischer-Stenger,K

文献摘要

被引文献

相似文献

大麻植物含有超过400种化学实体,其中60种或更多是大麻素(1)。δ-9-四氢大麻酚(Delta-9-tetrahydrocannabinol,THC)是大麻中主要的精神活性大麻素,在体内和体外均具有免疫抑制作用。该药物抑制淋巴细胞对有丝分裂原和颗粒抗原的反应性(2),减少T细胞玫瑰花结形成(3,4),抑制白细胞迁移(5),并改变巨噬细胞的形态、功能、运动性和蛋白质表达(6-8)。
The marijuana plant contains in excess of 400 chemical entities, of which 60 or more are cannabinoids (1). Delta-9-tetrahydrocannabinol (THC) is the major psychoactive cannabinoid in marijuana and has been shown to induce immunosuppressive effects bothin vivoandin vitro. The drug inhibits lymphocyte responsiveness to mitogens and particulate antigens (2), decreases T-cell rosette formation (3,4), suppresses leukocyte migration (5), and alters macrophage morphology, function, motility, and protein expression (6–8).