Marijuana and host resistance to herpesvirus infection.
Marijuana and host resistance to herpesvirus infection.
复制标题
大麻和宿主对疱疹病毒感染的抵抗力。
DOI:
10.1007/978-1-4615-2980-4_14
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发表时间:
1993
影响因子:
--
通讯作者:
Fischer-Stenger,K
中科院分区:
文献类型:
--
作者:
Cabral,GA;Pettit,DA;Fischer-Stenger,K
The marijuana plant contains in excess of 400 chemical entities, of which 60 or more are cannabinoids (1). Delta-9-tetrahydrocannabinol (THC) is the major psychoactive cannabinoid in marijuana and has been shown to induce immunosuppressive effects bothin vivoandin vitro. The drug inhibits lymphocyte responsiveness to mitogens and particulate antigens (2), decreases T-cell rosette formation (3,4), suppresses leukocyte migration (5), and alters macrophage morphology, function, motility, and protein expression (6–8).