Automatic registration of brain magnetic resonance images based on talairach reference system
Automatic registration of brain magnetic resonance images based on talairach reference system
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DOI：
10.1002/jmri.20168
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发表时间：
2004-10-01
影响因子：
4.4
通讯作者：
Park, HW
中科院分区：
文献类型：
--
作者：
Han, Y;Park, HW
目的：为了证明一种基于Talairach参考系统的脑磁共振图像的鲁棒配准方法，并自动确定基准点，材料和方法：从三维磁共振成像（MRI）数据中成功提取正中矢状面后，确定Talairach参考系统的8个指定标志点。利用图像强度的投影信息确定轴位和冠状位图像中大脑的中线，这是提取正中矢状面的必要步骤。为了找到前连合（AC）和后连合（PC）在正中矢状面的标志，我们采用两步形状匹配，正确地找到胼胝体（CC）的位置，然后AC和PC，分别。在边缘增强的中矢状平面图像上执行形状匹配，以最小化对图像强度变化的依赖性。结果：该方法能自动确定除下点（IP）以外的7个标志点，并能成功地将脑MR图像与Talairach参考系统进行配准。结论：该方法可应用于任何MR图像的功能研究。它也可以应用于患者，除非他们的大脑高度变形或具有高度变形的CC。
Purpose: To demonstrate a robust registration method of brain magnetic resonance (MR) images based on the Talairach reference system with automatic determinations of the fiducial points.Materials and Methods: Eight specified landmark points of the Talairach reference system are determined after suecessfully extracting the midsagittal plane from three-dimensional MR imaging (MRI) data. Projection information of the image intensity is used to determine the midline of the cerebrum in axial and coronal view images, which is a necessary step for extraction of the midsagittal plane. To find the landmarks of anterior commissure (AC) and posterior commissure (PC) in the midsagittal plane, we adopt two-step shape matching that properly finds locations of the corpus callosum (CC), and then AC and PC, respectively. The shape matching is performed on the edge-enhanced midsagittal plane image to minimize dependency on image intensity variation. Other landmark points of the Talairach reference system are determined by fitting the intensity curve of the cutview with the Gaussian model.Results: The proposed method automatically determines seven landmark points, except the inferior point (IP), and the brain MR images can be successfully registered with the Talairach reference system.Conclusion: The suggested registration method can be applied to any MR images for functional studies. It can also be applied to patients unless their brains are highly deformed or have a highly deformed CC.