NONSPECIFIC DEFENSE-MECHANISM - THE ROLE OF NITRIC-OXIDE

NONSPECIFIC DEFENSE-MECHANISM - THE ROLE OF NITRIC-OXIDE
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DOI:
10.1016/s0167-5699(05)80006-4
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发表时间:
1991-03-01
期刊:
IMMUNOPARASITOLOGY TODAY-A COMBINED ISSUE OF IMMUNOLOGY TODAY AND PARASITOLOGY TODAY
影响因子:
--
通讯作者:
COX, FEG
COX, FEG
中科院分区:
其他
文献类型:
--
作者:
LIEW, FY;COX, FEG

文献摘要

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适应性免疫反应的异常复杂性和特异性与其可以指导的效应器机制的数量有限之间存在明显的对比。最近,大量的兴趣集中在一氧化氮(NO)在这些机制之一的可能作用。这里F.Y. Liew和Frank考克斯研究了支持NO在寄生虫病中作用的证据,并提出了NO介导的寄生虫损伤的可能机制。
There is a marked contrast between the extraordinary complexity and specificity of the adaptive immune response and the limited number of effector mechanisms that it can direct. Recently, a great deal of interest has focused on the possible role of nitric oxide (NO) in one of these mechanisms. Here F.Y. Liew and Frank Cox examine the evidence supporting a role for NO in parasitic disease and suggest possible mechanisms of NO-mediated parasite damage.