Photoredox Catalysis in Organic Chemistry.
Photoredox Catalysis in Organic Chemistry.
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DOI：
10.1021/acs.joc.6b01449
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发表时间：
2016-08-19
期刊：
影响因子：
--
通讯作者：
MacMillan DW
中科院分区：
文献类型：
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作者：
Shaw MH;Twilton J;MacMillan DW
近年来，光氧化还原催化作为小分子活化的强大策略已成为有机化学的前沿。一般来说，这些方法依赖于金属配合物和有机染料通过与有机底物进行单电子转移，将可见光转化为化学能，从而产生反应中间体的能力。在本视角中，我们强调光氧化还原催化加速全新反应机制开发的独特能力，特别强调能够构建具有挑战性的碳-碳和碳-杂原子键的多催化策略。
In recent years, photoredox catalysis has come to the forefront in organic chemistry as a powerful strategy for the activation of small molecules. In a general sense, these approaches rely on the ability of metal complexes and organic dyes to convert visible light into chemical energy by engaging in single-electron transfer with organic substrates, thereby generating reactive intermediates. In this Perspective, we highlight the unique ability of photoredox catalysis to expedite the development of completely new reaction mechanisms, with particular emphasis placed on multicatalytic strategies that enable the construction of challenging carbon–carbon and carbon–heteroatom bonds.