Incidence and age distribution of colorectal cancer in Iran: Results of a population-based cancer registry
Incidence and age distribution of colorectal cancer in Iran: Results of a population-based cancer registry
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DOI：
10.1016/j.canlet.2005.09.004
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发表时间：
2006-08-18
期刊：
影响因子：
9.7
通讯作者：
Malekzadeh, Reza
中科院分区：
文献类型：
--
作者：
Ansari, Reza;Mahdavinia, Mahboobeh;Malekzadeh, Reza
伊朗结直肠癌(CRC)的流行病学模式尚未得到充分研究。在最近的癌症登记和积极的癌症监测中，我们收集了1996年至2000年伊朗五个省结直肠癌发病率的数据。总共有2055人在这项研究中登记。伊朗男性和女性的年龄调整CRC患病率分别为8.2/10万和7.0/100,000。在确诊时，17%的病例年龄在40岁以下。这一比例与许多其他中东国家的比例相似，但远高于西方国家的比例。伊朗和美国按年龄划分的发病率比较显示，年轻(40岁)的伊朗人和美国人的发病率相似，但年长的伊朗人(40岁)的发病率要低得多。我们的结论是，伊朗仍然是一个低风险的国家，尤其是对老年人来说。在伊朗，可能还有许多邻国，年轻的儿童结肠癌病例比例较高，这是因为这些国家的年龄结构较年轻，老年人的结直肠癌发病率相对较低。(C)2005爱思唯尔爱尔兰有限公司。保留所有权利。
Epidemiologic patterns of colorectal cancer (CRC) in Iran have not been studied adequately. In a recent cancer registry and active cancer surveillance, we collected data on the incidence of colorectal tumors in five provinces of Iran from 1996 to 2000. In total, 2055 were registered in this study. Age-adjusted rates of CRC in Iranian males and females were 8.2 and 7.0/100,000, respectively. Seventeen percent of the cases were younger than 40 years of age at the time of diagnosis. This proportion was similar to proportions seen in many other Middle-Eastern countries, but much higher than those seen in Western countries. A comparison of age-specific rates between Iran and the US showed similar rates in young (< 40 years) Iranians and Americans, but much lower rates in older (>= 40) Iranians.We conclude that Iran is still a country with low-risk of CRC, particularly for older individuals. The high proportions of young CRC cases seen in Iran, and probably many neighboring countries, are due to the young age-structure of these countries and relatively low rates of CRC in older individuals. (c) 2005 Elsevier Ireland Ltd. All rights reserved.