A Case of a Human-Papillomavirus-60-Induced Wart with Clinical Appearance of Both Pigmented and Ridged Warts
A Case of a Human-Papillomavirus-60-Induced Wart with Clinical Appearance of Both Pigmented and Ridged Warts
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一例人乳头瘤病毒 60 诱发的疣，临床表现为色素疣和脊状疣
作者：
Kiyofumi Egawa;S. Kasai;Naoko Hattori;Y. Saeki;M. Matsuda;H. Hino
人乳头瘤病毒（HPV）60型感染在组织学上与特征性同质胞浆内包涵体相关。然而，目前还不清楚该病毒是否与囊性、色素性或脊状足底疣有关。我们报告一位51岁的日本女性，因人类乳头瘤病毒60型感染而罹患足底疣，临床表现为色素疣及脊状疣。Masson-Fontana染色显示疣表皮中黑色素颗粒增多。这一观察结果表明，HPV-60可能不仅与囊性疣有关，而且与脊状疣的特定形态有关，色素沉着过度的生物学疾病可能受到其他未知因素的控制，这些因素因病例而异。
Human papillomavirus (HPV) type 60 infection is histologically associated with characteristic homogeneous intracytoplasmic inclusion bodies. However, it remains unclear whether the virus is associated with cystic, pigmented or ridged plantar warts. We report a 51-year-old Japanese female with a HPV-60-induced plantar wart which showed the clinical appearance of both pigmented and ridged warts. Masson-Fontana staining revealed increased melanin granules in the epidermis of the wart. This observation suggests that HPV-60 may be associated not only with cystic warts but also with the specific morphology of ridged warts, and the biological disorder of hyperpigmentation may be controlled by additional unknown factors which differ from case to case.