The effect of peripheral nerve lesions and of neonatal capsaicin in the rat on primary afferent depolarization
The effect of peripheral nerve lesions and of neonatal capsaicin in the rat on primary afferent depolarization
复制标题
大鼠周围神经损伤和新生辣椒素对初级传入去极化的影响
DOI：
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发表时间：
1982
期刊：
影响因子：
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通讯作者：
P. Wall
中科院分区：
文献类型：
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作者：
P. Wall
1.在周围神经完整的麻醉成年大鼠中，有髓传入神经的条件性顺向齐射产生了长期增加的兴奋性的终端的传入进行了顺向齐射和在终端的被动邻居。这种现象，初级传入去极化，通过在背角中用微电极逆向刺激传入神经以及通过在切断的外周神经上记录逆向齐射来显示。
1. In anaesthetized adult rats with intact peripheral nerves, a conditioning orthodromic volley in myelinated afferents produces a prolonged increase in the excitability of the terminals of the afferents which have carried the orthodromic volley and in the terminals of their passive neighbours. This phenomenon, primary afferent depolarization, p.a.d., is shown by the antidromic stimulation of afferents with a micro‐electrode in the dorsal horn and by recording the antidromic volley on a cut peripheral nerve.